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折扣/货期| 货号：GTX39939 | 规格：100μg | 目录价：￥6400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
IL4 Receptor / CD124 antibody [25463 (49/20)]
别名:
interleukin 4 receptor , CD124 , IL-4RA , IL4RA
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FCM, IHC-P, WB
同种型:
IgG1
免疫原:
Spodoptera frugiperda lepidopteran ovarian cell line Sf21-derived, recombinant human interleukin 4 receptor, extracellular domain.
克隆性:
Monoclonal
克隆号:
25463 (49/20)
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% Trehalose, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
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