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折扣/货期| 货号：GTX47438 | 规格：50μg | 目录价：￥6100 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
INSIG1 antibody, Internal
别名:
insulin induced gene 1 , CL6
反应种属:
Human, Rat
宿主来源:
Rabbit
实验应用:
IHC-P, WB
同种型:
IgG
免疫原:
A synthetic peptide corresponding to an Internal region of Human INSIG1
克隆性:
Polyclonal
克隆号:
纯化方式:
Affinity Purified
偶联:
Unconjugated
产品浓度:
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
30
产品形式:
Liquid
存储溶液:
PBS, 2% Sucrose, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes an endoplasmic reticulum membrane protein that regulates cholesterol metabolism, lipogenesis, and glucose homeostasis. The encoded protein has six transmembrane helices which contain an effector protein binding site. It binds the sterol-sensing domains of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase), and is essential for the sterol-mediated trafficking of these two proteins. It promotes the endoplasmic reticulum retention of SCAP and the ubiquitin-mediated degradation of HMG-CoA reductase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
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