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折扣/货期| 货号：GTX28305 | 规格：100μg | 目录价：￥4300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Insulin antibody [D3E7]
别名:
insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10
反应种属:
Bovine, Human, Mouse, Pig, Rat
宿主来源:
Mouse
实验应用:
ELISA, IHC-Fr
靶标/特异性:
Clone D6C4 and D3E7 directed to different antigenic determinants. Kd is 8.1 x 10⁻⁸M. This antibody reacts with insulin/proinsulin but does not react with free C-peptide.
同种型:
IgG1
免疫原:
Synthetic peptide, Immunogen sequence information is commercially sensitive.
克隆性:
Monoclonal
克隆号:
D3E7
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
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