| 货号:GTX44185 | 规格:100μg | 目录价:¥6000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Integrin alpha 4 antibody [HP2.1]
别名:
integrin subunit alpha 4 , CD49D , IA4
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM, IM
靶标/特异性:
The molecular weight of the recognized antigen is 150 kDa. CD49d antigen is the integrin alpha-4 chain non-covalently associated with the integrin beta-1-chain (CD29 molecule) forming the VLA4 complex. Reacts with monocytes, T cells, B cells, thymocytes and Langerhans cells.
同种型:
IgG1
免疫原:
M Leukemia Line
克隆性:
Monoclonal
克隆号:
HP2.1
纯化方式:
Purified IgG
偶联:
Unconjugated
产品浓度:
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, no preservatives.
生产商:
GeneTex
功能与背景:
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
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