| 货号:GTX75041 | 规格:200μg | 目录价:¥6500 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Integrin beta 4 antibody [450-9D]
别名:
integrin subunit beta 4 , CD104 , GP150
反应种属:
Ferret, Human, Mustelid
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, IHC-Fr, IP, WB
靶标/特异性:
This antibody recognizes an extracellular epitope on Integrin beta 4.
同种型:
IgG1
免疫原:
Purified alpha6 beta4 integrin from A431 cells.
克隆性:
Monoclonal
克隆号:
450-9D
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1.0 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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