IRF7 antibody-多抗-深圳欣博盛生物科技有限公司

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IRF7 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX85490

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

IRF7 antibody

别名:

interferon regulatory factor 7 , IMD39 , IRF-7 , IRF-7H , IRF7A , IRF7B , IRF7C , IRF7H

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ELISA, IHC-P, WB

靶标/特异性:

This antibody is specific for IRF7 C-Terminus

同种型:

IgG

免疫原:

IRF7 antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human IRF7.The immunogen is located within amino acids 420 - 470 of IRF7.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.

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