深圳欣博盛生物科技有限公司 a1

JG-2016
货号:41876-1 mg 规格:1 mg 目录价:¥1112
货号:41876-10 mg 规格:10 mg 目录价:¥7196
货号:41876-25 mg 规格:25 mg 目录价:¥13829
货号:41876-5 mg 规格:5 mg 目录价:¥4703
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
JG-2016
产品描述:
A HAT1 inhibitor (IC50 = 14.8 µM); selective for HAT1 over KAT2A and p300/CBP-associated factor (PCAF), for which it has no activity, KAT5, KAT6B, and KAT7 (IC50s = >100, >100, and 84.82 µM, respectively), CBP, and p300 (IC50s = 90.41 and 74.25 µM, respectively); reduces acetylation of H4K5 and H4K12 in hTert-HME1 mammary epithelial cells at 20 µM; reduces the growth of HCC1806 and A549 cells (EC50s = 10.4 and 1.9 µM, respectively); reduces intratumoral H4K12 acetylation in an A549 mouse xenograft model in a dose-dependent manner; reduces tumor growth in an A549 mouse xenograft model at 50 and 100 mg/kg once every three days
保存温度:
-20
运输温度:
-20
预期分子量:
376.8372
产品形式:
A solid
纯度:
≥98%
CAS号:
2887480-87-5
分子式:
C18H21ClN4O3
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