深圳欣博盛生物科技有限公司 a1

LMTK3 Inhibitor C28
货号:41877-10 mg 规格:10 mg 目录价:¥1836
货号:41877-100 mg 规格:100 mg 目录价:¥13413
货号:41877-5 mg 规格:5 mg 目录价:¥965
货号:41877-50 mg 规格:50 mg 目录价:¥7665
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
LMTK3 Inhibitor C28
别名:
Lemur Tyrosine Kinase 3 Inhibitor 1|Lemur Tyrosine Kinase Inhibitor C28|Lemur Tyrosine Kinase-IN-C28|LMTK3 Inhibitor 1|LMTK3-IN-1|LMTK3-IN-C28
产品描述:
A multi-kinase inhibitor; inhibits LMTK3, Clk2, DYRK1α, HIPK2, and IRAK4 (IC50s = 67, 5, 6, 48, and 41 nM), among others; selective for these kinases over a panel of 122 kinases at 1 µM; induces proteasomal degradation of LMTK3 in MCF-7, T47D, and MDA-MB-231 cells at 5 or 10 µM; reduces the levels of IRAK4, ERα, phosphorylated TrkA, and HIPK2 in T47D cells at 10 µM; induces apoptosis in MCF-7, T47D, and MDA-MB-231 cells at 10 µM; reduces tumor growth and volume in an MDA-MB-231 mouse xenograft model at 10 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
356.301509
产品形式:
A solid
纯度:
≥98%
CAS号:
2764850-23-7
分子式:
C18H11F3N4O
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