深圳欣博盛生物科技有限公司 a1

K29-linked Tetra-Ubiqutin (human) (rec.) (untagged)
货号:SBB-UP0078-C025 规格:25 ug 目录价:¥3332
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
K29-linked Tetra-Ubiqutin (human) (rec.) (untagged)
别名:
Ub4
产品描述:
The array of cellular processes initiated and regulated by ubiquitin has been partially explained by the structural diversity of differently linked ubiquitin chains. In a ubiquitin chain, ubiquitin moieties can be conjugated through one of their lysine residues (K6, K11, K27, K29, K33, K48 and K63) or the N-terminal methionine residue (M1), offering countless possibilities to assemble a specific polymer. Ubiquitin molecules can also be modified by other post-translational modifications, including acetylation and phosphorylation, adding another layer of ubiquitin signal regulation and diversification. K29-linked polyubiquitination has been shown to be an inhibitor of Wnt signaling, which plays an important role in embryogenesis, and its deregulation has been shown to play a role in tumorigenesis. This protein is formed with wild-type human recombinant ubiquitin and linkage-specific enzymes. Ideal for investigating ubiquitin-binding proteins and as substrates for ubiquitin-specific isopeptidases. Reaction conditions will need to be optimized for each specific application.
宿主来源:
E. coli
产品浓度:
Lot dependent.
保存温度:
-80°C
运输温度:
Dry Ice
预期分子量:
~34kDa
产品形式:
liquid
存储溶液:
Liquid. In 50mM HEPES pH 7.5.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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