K777 [K11777]-抑制剂-深圳欣博盛生物科技有限公司

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K777 [K11777]

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-0158-M001	规格：1 mg	目录价：￥540
货号：AG-CR1-0158-M005	规格：5 mg	目录价：￥2160

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

K777 [K11777]

别名:

K-777; K-11777; N-Pip-F-hF-VS Phenyl; N-Pip-phenylalanine-homophenylalanine-vinyl sulfone phenyl; N-Methyl-piperazinyl-L-phenylalanyl-L-homophenylalanyl-vinyl sulfone

产品描述:

Broad-range cathepsin inhibitor (for all known cathepsins) useful for inflammasome inhibition. Inhibits cathepsins B, L, S, C, V, K and papain in cell-free assays. Inhibits cathepsin X as well. Suppresses particle-induced NLRP3 activation and IL-1beta secretion more efficiently than Ca074Me (cathepsin B inhibitor), which in contrast suppresses nigericin-induced IL-1beta secretion. Selectively inhibits particle-induced cell death but not nigericin- or sAdT-induced cell death. Potent and selective CCR4 antagonist. Potent, irreversible cysteine protease inhibitor. Potent cysteine protease cruzain (cruzipain) inhibitor. Active against Trypanosoma cruzi the causative agent of Chagas' disease, a parasitic infection which is a leading cause of heart disease. Antiparasitic agent with anti-trypanosomal , anti-leishmanial, anti-schistosomiasis, anti-amebiasis (EhCP1 (E. Histolytica cysteine proteinase 1)), anti-anthelmintic (hookworm first-stage larvae) and anti-cryptosporidial activity. Shown to have antiviral activity by targeting cathepsin-mediated cell entry.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

574.7

产品形式:

solid

产地:

瑞士

纯度:

>98% (NMR)