| 货号:V8796-100UG | 规格:100 ug | 目录价:¥6652.1 |
| 货号:V8796-20UG | 规格:20 ug | 目录价:¥3082.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Keratin 17 Antibody / Cytokeratin 17 / CK17
产品描述:
Cytokeratin 17 (CK17) is normally expressed in the basal cells ofcomplex epithelia but not in stratified orsimple epithelia. Antibody to CK17 is an excellent tool to distinguish myoepithelial cells from luminal epithelium of various glandssuch as mammary, sweat and salivary. CK17 is expressed in epithelial cells of various origins, such as bronchial epithelial cells and skin appendages. It may be considered as epithelial stem cell marker because CK17 Ab marks basal cell differentiation. CK17 is expressed in SCLC much higher than in LADC. Eighty-five percent of the triple negative breast carcinomas immunoreact with basal cytokeratins including anti-CK17. Also important is that cases of triple negative breast carcinoma with expression of CK17 show an aggressive clinical course. Additionally, anti-CK17 and anti-MUC1 immunoreactivity represents pancreatobiliary subtype whereas anti-MUC2 and anti-CDX-2 positivity defines intestinal subtype.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
Rabbit IgG
免疫原:
Recombinant full-length human KRT17 protein was used as the immunogen for the Keratin 17 antibody.
克隆性:
Recombinant Rabbit Monoclonal
克隆号:
KRT17/7155R
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the Keratin 17 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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