KIF3A antibody-多抗-深圳欣博盛生物科技有限公司

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KIF3A antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX11259

规格：50μl

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

KIF3A antibody

别名:

kinesin family member 3A , FLA10 , KLP-20

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

IHC-P, WB

同种型:

IgG

免疫原:

synthetic peptide corresponding to the C-terminus of mouse KIF3A (amino acids 682-701) conjugated to KLH.

克隆性:

Polyclonal

克隆号:

纯化方式:

IgG fraction

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 15mM Sodium azide.

生产商:

GeneTex

功能与背景:

The kinesin superfamily (KIFs) of proteins consists of a class of microtubule-dependent motors that plays a major role in many cellular and developmental functions, including organelle transport, mitosis, meiosis, and possibly long-range signaling in neurons. The KIF proteins are primarily associated with anterograde transport of vesicles and organelles in neurons, epithelial cells, and melanosomes with bidirectional transport of mitochondria and mediating transport between the endoplasmic reticulum (ER) and the Golgi complex. KIF3 motor complex is composed of the KIF3A, KIF3B, and KIF3C motor subunits, that associate as heterodimers, in which KIF3B and KIF3C are alternative partners of KIF3A. KIF3A/B has been shown to function in vivo as a motor for the anterograde fast axonal transport of membranebound organelles in neurons. KIF3 plays a crucial role during development. KIF3A-/- and KIF3B-/- mice do not survive beyond midgestation.

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