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折扣/货期| 货号：GTX31949 | 规格：100μg | 目录价：￥6200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
KIR2DS2 antibody
别名:
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 , 183ActI , CD158J , CD158b , KIR-2DS2 , NKAT-5 , NKAT5 , cl-49
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ELISA, ICC/IF, WB
靶标/特异性:
KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.
同种型:
IgG
免疫原:
KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2.The immunogen is located within the last 50 amino acids of KIR2DS2.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
预期分子量:
34
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are
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