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折扣/货期| 货号：7261-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：7261-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
KREMEN1 Antibody
别名:
KREMEN1 Antibody: KRM1, KREMEN, KRM1, Kremen protein 1, Dickkopf receptor
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
ELISA,WB,IHC-P,IF
靶标/特异性:
Three isoforms of KREMEN1 exists as a result of alternative splicing event.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
KREMEN1 Antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
KREMEN1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
KREMEN1 Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
KREMEN1 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) coreceptor. KREMEN1 is a receptor for the Dickkopf protein which blocks Wnt/beta catenin signaling. It is necessary to ensure normal spatial and temporal patterns of Wnt activity during developmental processes.
Accession #:
NP_114434
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