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折扣/货期| 货号：7263-0.02 mg | 规格：0.02 mg | 目录价：￥1345.5 |
| 货号：7263-0.1 mg | 规格：0.1 mg | 目录价：￥6084 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
KREMEN2 Antibody
别名:
KREMEN2 Antibody: KRM2, KRM2, Kremen protein 2, Dickkopf receptor 2
反应种属:
Human,Mouse,Rat
宿主来源:
Rabbit
实验应用:
ELISA,WB,ICC
靶标/特异性:
Multiple isoforms of KREMEN2 are known to exist. KREMEN2 antibody is predicted to not cross-react with other Kremen protein family members.
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
KREMEN2 Antibody is affinity chromatography purified via peptide column.
偶联:
Unconjugated
产品浓度:
1 mg/mL
保存温度:
KREMEN2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
KREMEN2 Antibody is supplied in PBS containing 0.02% sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
KREMEN2 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) co-receptor. Recent experiments have shown that KREMEN2 is a regulator of bone remodeling and raise the possibility that antagonizing KREMEN2 might prove beneficial in patients with bone loss disorders.
Accession #:
NP_757384
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