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折扣/货期| 货号：9002528-10 mg | 规格：10 mg | 目录价：￥1701.8 |
| 货号：9002528-5 mg | 规格：5 mg | 目录价：￥924.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
KRIBB11
产品描述:
An Hsf1 inhibitor (IC50 = 1.2 μM in a luciferase reporter assay); blocks heat shock-induced Hsp70, Hsp40, and Hsp27 mRNA expression and down-regulates protein expression of the Hsf1 target proteins Hsp70 and Hsp27 in HCT116 cells in a dose-dependent manner; specifically binds to Hsf1 over other Hsf1-associated proteins, lacking activity at Hsp90, Hsf2, and Cdk9 in an in vitro pull-down assay; inhibits growth of cancer cell lines (IC50s = 3-8 μM) via induction of cell cycle arrest at the G2/M phase and apoptosis; decreases tumor growth in a mouse HCT116 xenograft model; attenuates dengue virus progression and reduces mortality in infected mice
保存温度:
-20
运输温度:
-20
预期分子量:
284.3
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥95%
CAS号:
342639-96-7
分子式:
C13H12N6O2
促销活动
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