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折扣/货期| 货号：GTX45122 | 规格：100μg | 目录价：￥4000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
KSHV GPCR antibody
别名:
Kaposi's sarcoma-associated herpesvirus GPCR , HHV-8 GPCR , Human herpesvirus 8 GPCR
反应种属:
Kaposi's sarcoma-associated herpesvirus
宿主来源:
Rabbit
实验应用:
FCM
同种型:
IgG
免疫原:
Recombinant fragment - amino acids 1-41 of HHV8 GPCR (N-terminal)
克隆性:
Polyclonal
克隆号:
纯化方式:
Protein A affinity purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
Kaposi's sarcoma-associated herpesvirus (KSHV, or human herpesvirus 8, HHV8), is a gamma herpesvirus that contain an open reading frame encoding a G protein-coupled receptor (GPCR) with putative 7 transmembrane domains. This GPCR has been shown to bind a number of chemokines including IL8, NAP2, PF4, MGSA/Gro alpha, I309, RANTES, MCP1, and MIP1 beta. The receptor is constitutively activated without chemokine binding, and it stimulates cell proliferation. KSHV GPCR is also a viral oncogene that stimulates angio-genesis through induction of VEGF expression. IP10, a chemokine, can inhibit constitutively activated KSHV GPCR.
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