| 货号:V9740-100UG | 规格:100 ug | 目录价:¥6652.1 |
| 货号:V9740-20UG | 规格:20 ug | 目录价:¥3082.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Ku80 Antibody / XRCC5
产品描述:
The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 or (p86) which is also known by the synonym Ku-80 or (p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Ku has several functions, including cell signaling, DNA replication and transcriptional activation. Ku is involved in Pol II-directed transcription by virtue of its DNA binding activity; serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters.
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, IHC-P
同种型:
Mouse IgG1, kappa
免疫原:
A portion of amino acids 300-500 was used as the immunogen for the Ku80 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
XRCC5/7317
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the Ku80 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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