Ku80 Antibody / XRCC5-单抗-深圳欣博盛生物科技有限公司

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Ku80 Antibody / XRCC5

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9740SAF-100UG

规格：100 ug

目录价：￥6414.1

产品详情

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产品名称:

Ku80 Antibody / XRCC5

产品描述:

The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 or (p86) which is also known by the synonym Ku-80 or (p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Ku has several functions, including cell signaling, DNA replication and transcriptional activation. Ku is involved in Pol II-directed transcription by virtue of its DNA binding activity; serving as the regulatory component of the DNA-associated protein kinase that phosphorylates Pol II and transcription factor Sp. Ku proteins also activate transcription from the U1 small nuclear RNA and the human transferrin receptor gene promoters.

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB, IHC-P

同种型:

Mouse IgG1, kappa

免疫原:

A portion of amino acids 300-500 was used as the immunogen for the Ku80 antibody.

克隆性:

Monoclonal (mouse origin)