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折扣/货期| 货号：AG-40B-0039-C050 | 规格：50 ug | 目录价：￥4080 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
LAG-3 (mouse):Fc (mouse) (rec.)
别名:
Lymphocyte Activation Gene-3; FDC Protein; CD223
产品描述:
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
宿主来源:
CHO cells
靶标/特异性:
Binds to human and mouse MHC class II.
产品浓度:
0.5 mg/ml
保存温度:
-20°C
运输温度:
DI
预期分子量:
~180kDa (SPS-PAGE, nonreducing), ~80kDa (SPS-PAGE, reducing)
产品形式:
liquid
存储溶液:
Liquid. In PBS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Induces maturation of mouse dendritic cells in vitro. Induces CD4 and CD8 antigen-specific T cells responses when coinjected s.c. in mice, together with the antigen.
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
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