官网链接
折扣/货期| 货号：11493-10 mg | 规格：10 mg | 目录价：￥1085 |
| 货号：11493-100 mg | 规格：100 mg | 目录价：￥3564 |
| 货号：11493-25 mg | 规格：25 mg | 目录价：￥1648 |
| 货号：11493-5 mg | 规格：5 mg | 目录价：￥844 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Lapatinib
别名:
GSK 572016|GW 572016
产品描述:
A dual inhibitor of EGFR and ErbB2 (IC50s = 19 and 3 nM, respectively); inhibits the growth of EGFR-overexpressing A431 skin cancer and ErbB2-overexpressing SK-BR-3 breast cancer cells (IC50s = 0.14 and 0.124 μM, respectively); inhibits the growth of ErbB2-amplified OD19 esophageal and NCI-N87 gastric cancer cells (IC50s = 0.09 and 0.01 μM, respectively); inhibits the growth of gastric cancer cells in which ErbB2 is not amplified (IC50s = 0.35-8.58 μM); induces apoptosis in NCI-N87 and OD19 cells at 1 μM; reduces tumor growth in a BT474 breast cancer mouse xenograft model at 50 mg/kg; reduces tumor growth in an NCI-N87 mouse xenograft model at 100 mg/kg and induces tumor regression when used in combination with trastuzumab
保存温度:
-20
运输温度:
-20
预期分子量:
581.1
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
231277-92-2
分子式:
C29H26ClFN4O4S
促销活动
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