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折扣/货期| 货号：GTX642087 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX642087-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Latrophilin 1 antibody [HL3853]
别名:
adhesion G protein-coupled receptor L1 , CIRL1 , CL1 , LEC2 , LPHN1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody detects both full-length Latrophilin 1 as well as the C-terminal fragment Latrophilin 1 form.<br>This antibody was raised against human Latrophilin 1 Extracellular domain.
同种型:
IgG
免疫原:
Synthetic peptide encompassing a sequence within the Intracellular domain of human Latrophilin 1. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL3853
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
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