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折扣/货期| 货号：SIH-368-50MG | 规格：50 mg | 目录价：￥706 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Leflunomide
别名:
5-methyl-N-[4-(trifluoromethyl) phenyl]-isoxazole-4-carboxamide
产品描述:
Immunosupressant
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
270.21
产品形式:
White crystalline solid
产地:
加拿大
功能与背景:
Leflunomide is an Immuno-suppressant, it inhibits de novo synthesis of pyrimidine nucleotides and the activity of the protein kinase. It is a part of the known “disease-modifying anti-rheumatic drugs” (DMARD). It has been suggested that leflunomide modulates the expansion of activated autoimmune lymphocytes acting on the regression of rheumatoid conditions (1-2). It has been shown to have a double mechanism of action by slowing down and relieving the pain of rheumatoid arthritis. Studies have shown the lethal effects of Leflunomide after administration to mice in various doses (3).
纯度:
>98% (TLC: 5:95, CH3OH/CH2Cl2; Rf=0.65); NMR (Conforms)
来源:
Synthetic
CAS号:
75706-12-6
分子式:
C12H9F3N2O2
溶解度:
May be dissolved in DMSO (30 mg/ml); or Ethanol (27 mg/ml)
PubChem CID:
3899
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