| 货号:SIH-410-50MG | 规格:50 mg | 目录价:¥3715 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Lenalidomide
别名:
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
产品描述:
Ubiquitin ligase inducer
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
259.26
产品形式:
Powder
产地:
加拿大
功能与背景:
Clinically, lenalidomide has proven to be effective in the treatment of multiple myeloma and other B cell diseases. It has the ability to selectively bind and ubiquitinate two lymphoid transcription factors, IKZF1 and IKZF2, via the CRBN-CRL4 ubiquitin ligase. This ultimately leads to the degradation of IKZF1 and IKZF2, which are both essential in myeloma cell survival.
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
191732-72-6
分子式:
C13H13N3O3
溶解度:
Soluble in DMSO (200 mM), Water (<1 mM) and Ethanol (<1 mM).
PubChem CID:
216326
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