| 货号:24085-1 mg | 规格:1 mg | 目录价:¥844 |
| 货号:24085-10 mg | 规格:10 mg | 目录价:¥4864 |
| 货号:24085-5 mg | 规格:5 mg | 目录价:¥2720 |
| 货号:24085-500 µg | 规格:500 µg | 目录价:¥482 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Linaclotide
产品描述:
A peptide agonist of the guanylate cyclase C receptor (Ki = 16.4 nM in a radioligand binding assay using mouse intestinal mucosa); stimulates fluid secretion and cGMP concentration in jejunal loops isolated from wild-type mice but not guanylate cyclase C receptor-null mice; increases intestinal transit rate in wild-type mice when administered at a dose of 100 μg/kg; reduces the number of phosphorylated ERK-positive dorsal horn neurons in the thoracolumbar spinal cord, a marker of nociceptive signaling, following noxious colorectal distension and mechanical hypersensitivity in a mouse model of TNBS-induced colitis
保存温度:
-20
运输温度:
-20
产品形式:
A solid
纯度:
≥95%
CAS号:
851199-59-2
分子式:
C59H79N15O21S6
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