深圳欣博盛生物科技有限公司 a1

Pasireotide (aspartate) (trifluoroacetate salt)
货号:24092-1 mg 规格:1 mg 目录价:¥2332
货号:24092-10 mg 规格:10 mg 目录价:¥15008
货号:24092-5 mg 规格:5 mg 目录价:¥9246
产品详情
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产品名称:
Pasireotide (aspartate) (trifluoroacetate salt)
别名:
SOM230
产品描述:
An SSTR agonist; binds selectively to human SST1, SST2, SST3, and SST5 over SST4 (IC50s = 9.3, 1, 1.5, 0.16, and >100 nM, respectively, for human recombinant receptors); dose-dependently inhibits GHRH-stimulated growth hormone release by primary rat anterior pituitary cells; inhibits ACTH secretion by some primary human corticotrope adenomas (10 nM); inhibits ACTH release and proliferation by mouse AtT20 pituitary corticotrope cells in vitro (10 nM); inhibits tumor growth of subcutaneously implanted AtT20 cells in vivo in nude mice (1.5 μg per day); decreases plasma ACTH concentrations and tumor size in dogs with ACTH-dependent Cushing’s disease (0.03 mg/kg)
保存温度:
-20
运输温度:
-20
预期分子量:
1047.2
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
3002987-80-3
分子式:
C58H66N10O9 • 2C4H7NO4 • XCF3COOH
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