货号:AG-CP3-0034-M001 | 规格:1 mg | 目录价:¥660 |
货号:AG-CP3-0034-M005 | 规格:5 mg | 目录价:¥1740 |
货号:AG-CP3-0034-M025 | 规格:25 mg | 目录价:¥4320 |
货号:AG-CP3-0034-M100 | 规格:100 mg | 目录价:¥10560 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Liraglutide
产品描述:
Long-acting acylated glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic and antiobesity agent used clinically to treat type 2 diabetes mellitus. Binding to GLP-1R, activates AMP-activated protein kinase, consequently stimulates insulin secretion in pancreatic beta cells and suppresses glucagon secretion in a glucose-dependent manner. Improves control of blood glucose and consequently modulates appetite and body weight. Inhibits beta cell apoptosis and improves beta cell mass. Shown to ameliorate glycometabolism and insulin resistance through the upregulation of GLUT4. Neuroprotective. Prevents neurodegenerative processes in pathologies such as Alzheimer's and Parkinsons Disease. Anti-inflammatory agent. Exerts cardioprotective roles via activating prosurvival pathways and suppressing inflammation. Anti-pyroptotic by inhibiting TNF-alpha and hypoxia-induced inflammasome activation. Anticancer agent. Inhibited proliferation and induced apoptosis in cancer cell lines. Shown to inhibit osteoclastogenesis.
宿主来源:
Synthetic.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
3751.2
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
204656-20-2
分子式:
C172H265N43O51
溶解度:
Freely soluble in aqueous base (>pH7). Soluble in methanol (20mg/ml) and slightly soluble in DMSO or ethanol (1mg/ml).
促销活动
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