| 货号:33-540 | 规格:100 ug | 目录价:¥10986.3 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Macrophage / Histiocytoma Marker Antibody [D11]
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
靶标/特异性:
Does not react with Mouse, Rat, Pig
同种型:
IgG1, kappa
克隆性:
Monoclonal
克隆号:
D11
纯化方式:
Protein G affinity chromatography
偶联:
Unconjugated
产品浓度:
0.2 mg/mL
保存温度:
Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
产地:
美国
生产商:
Prosci
功能与背景:
In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this mAb and a standard CD68 mAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This mAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This mAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
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