MASPIN Antibody / SERPINB5-单抗-深圳欣博盛生物科技有限公司

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MASPIN Antibody / SERPINB5

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9709SAF-100UG

规格：100 ug

目录价：￥6414.1

产品详情

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产品名称:

MASPIN Antibody / SERPINB5

产品描述:

Maspin is structurally a serine protease inhibitor (serpin) that was initially isolated from normal human mammary epithelial cells. Serpins are a family of proteins that inhibit Chymotrypsin-like serine proteinases. Serpins control activated proteinases and several are involved in the regulation of cell death. Maspin is found in the extracellular matrix and at the plasma membrane. Maspin has been shown to act at the cell surface to block cell motility and inhibit invasion of breast and prostate cancer cells. Maspin is present in normal mammary epithelial cells but is absent in many tumor cell lines, yet no major structural alterations of the Maspin gene have been identified in tumor cells. Similarly, Maspin is expressed in normal prostate cells and downregulated or absent in prostate tumor cells.

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB, IHC-P

同种型:

Mouse IgG1, kappa

免疫原:

A portion of amino acids1-200 was used as the immunogen for the MASPIN antibody.

克隆性:

Monoclonal (mouse origin)