官网链接
折扣/货期| 货号：AG-CR1-3907-M001 | 规格：1 mg | 目录价：￥1800 |
| 货号：AG-CR1-3907-M005 | 规格：5 mg | 目录价：￥7200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MBIMPH
别名:
N-Hydroxy-4-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)benzamide
产品描述:
Cell permeable, potent and selective class IIb HDAC6 inhibitor (IC50 =9nM). Displays high selectivity over all other HDACs (IC50=0.1-12µM). Induces cellular alpha-tubulin, but not histone H3 hyperacetylation in Neuro-2a cells. Promotes mitochondrial transport. Shows improved kinetics and biochemical potency against HDAC6 compared to tubastatin A (Prod. No. AG-CR1-3900). HDAC6 deacetylates tubulin, HSP90 and the core histones (H2A, H2B, H3, H4). Histone deacetylases act via the formation of large multiprotein complexes. HDAC6 plays an important role in microtubule-dependent cell motility, transcriptional regulation, degradation of misfolded proteins and cell cycle and is involved in autophagy, inflammation, cancer and neurodegeneration.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
281.3
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
1392835-53-8
分子式:
C16H15N3O2
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