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折扣/货期| 货号：27658-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：27658-10 mg | 规格：10 mg | 目录价：￥2492 |
| 货号：27658-25 mg | 规格：25 mg | 目录价：￥5628 |
| 货号：27658-5 mg | 规格：5 mg | 目录价：￥1608 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Methysergide (maleate)
别名:
Desernil|NSC 186061
产品描述:
A 5-HT1 receptor agonist and 5-HT2 receptor antagonist; binds to recombinant human 5-HT1A (KD = 23.44 nM), 5-HT1E (Ki = 229.09 nM), 5-HT1F (Ki = 33.88 nM), and rodent 5-HT1B receptors (KD = 1,513.56 nM); binds to recombinant human 5-HT2A (Ki = 2.69 nM) and 5-HT2C receptors (KD = 1.26 nM) and is an insurmountable antagonist at 5-HT2B receptors; inhibits 5-HT-induced vasoconstriction in isolated postmortem human basilar arterial spiral strips (pA2 = 8.07); decreases external carotid blood flow in a dose-dependent manner in vagosympathectomized dogs; has antinociceptive activity in mouse models of pain induced by substance P, glutamate, NMDA, AMPA, or kainic acid; reduces zymosan-induced paw edema in rats at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
353.4581
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
129-49-7
分子式:
C21H27N3O2 • C4H4O4
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