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折扣/货期| 货号：GTX71001 | 规格：25μg | 目录价：￥3800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
mGluR8 antibody
别名:
glutamate metabotropic receptor 8 , GLUR8 , GPRC1H , GRM8 , MGLUR8 , mGlu8 , mGluR8 , Metabotropic Glutamate Receptor 8
反应种属:
Bat, Horse, Human, Monkey, Mouse, Rat
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
IgG
免疫原:
Synthetic 19 amino acid peptide from C-terminus of human GRM8 / MGLUR8.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.79 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
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