MHC class I antigen G Antibody / HLA-G-单抗-深圳欣博盛生物科技有限公司

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MHC class I antigen G Antibody / HLA-G

品牌：NSJ Bio

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说明书

折扣/货期

货号：V5734SAF-100UG

规格：100 ug

目录价：￥6652.1

产品详情

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产品名称:

MHC class I antigen G Antibody / HLA-G

产品描述:

Major histocompatibility complex (MHC), human leukocyte antigen (HLA) molecules are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an a or heavy chain, and a non-covalently associated protein, Î²2-microglobulin. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a noncovalent complex of an a and b chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG1, kappa

免疫原:

A portion of amino acids 1-200 from human HLAG protein was used as the immunogen for the MHC class I antigen G antibody.

克隆性:

Monoclonal (mouse origin)