货号:37332-10 mg | 规格:10 mg | 目录价:¥2940 |
货号:37332-25 mg | 规格:25 mg | 目录价:¥6174 |
货号:37332-5 mg | 规格:5 mg | 目录价:¥1554 |
货号:37332-50 mg | 规格:50 mg | 目录价:¥10038 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MKC8866
别名:
Inositol-Requiring Enzyme 1α Inhibitor 8866|IRE1-IN-8866
产品描述:
An inhibitor of IRE1α RNase activity (IC50 = 0.29 µM); inhibits DTT-induced production of XBP1 in MM.1S multiple myeloma cells (EC50 = 0.52 µM) and thapsigargin-induced XBP1 production in LNCaP cells (IC50 = 0.38 µM); decreases expression of the XBP1 target genes SREBF1, DGAT2, and LIPE and increases triglyceride levels in MDA-MB-231 cells; reduces tumor volume in LNCaP, VCaP, 22Rv1, and C4-2B prostate cancer mouse xenograft models at 300 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
361.4
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1338934-59-0
分子式:
C18H19NO7
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