| 货号:GTX86916 | 规格:100μg | 目录价:¥5300 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MMP14 (cleaved Tyr112) antibody
别名:
MMP14 , MMPX1 , MT1MMP , MTMMP , MTMMP 1 , MTMMP1 , WNCHRS , matrix metallopeptidase 14
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
MMP14 (cleaved Tyr112) antibody detects endogenous levels of fragment of activated MMP14 resulting from cleavage adjacent to Tyr112.
同种型:
IgG
免疫原:
The antiserum was produced against synthesized peptide derived from human MMP14 (93-142).
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]
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