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折扣/货期| 货号：GTX30147 | 规格：100μl | 目录价：￥6700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MMP2 antibody [8B4]
别名:
matrix metallopeptidase 2 , CLG4 , CLG4A , MMP-2 , MMP-II , MONA , TBE-1
反应种属:
Human, Mouse, Paracentrotus lividus, Rat
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, IHC-Fr, IHC-P, IP, WB
靶标/特异性:
This is specific for pro and active MMP2.
同种型:
IgG1
免疫原:
Activated recombinant human MMP2. [UniProt# P08253]
克隆性:
Monoclonal
克隆号:
8B4
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
74
产品形式:
Liquid
存储溶液:
PBS, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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