| 货号:V7437SAF-100UG | 规格:100 ug | 目录价:¥6652.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
MMP3 Antibody
产品描述:
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP3, MMP10 and MMP11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP3 activation of procollagenase can occur via two pathways. Direct activation by MMP3 is slow and activation by MMP3 in conjunction with tissue or plasma proteinases is rapid. MMP10 is expressed in small intestine, and at lower levels in lung and heart. MMP11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, WB
同种型:
Mouse IgG2b, kappa
免疫原:
A portion of amino acids 236-363 was used as the immunogen for the MMP3 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
MMP3/2655
纯化方式:
Protein G affinity chromatography
保存温度:
Store the MMP3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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