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折扣/货期| 货号：GTX01886 | 规格：500μl | 目录价：￥4500 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Mouse Anti-Human lambda light chain antibody [SHL53]
别名:
immunoglobulin lambda locus , IGL@ , IGLC6
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
同种型:
IgG1
免疫原:
Prokaryotic recombinant protein corresponding to 105 amino acids of the human lambda light chain molecule.
克隆性:
Monoclonal
克隆号:
SHL53
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tissue culture supernatant, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq, Jul 2008]
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