Mouse Prr5 Antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

Mouse Prr5 Antibody

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：60-482

规格：400 ul

目录价：￥8687.25

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Mouse Prr5 Antibody

别名:

Proline-rich protein 5, Protein observed with Rictor-1, Protor-1, Prr5 {ECO:0000250|UniProtKB:P85299}, Protor1

反应种属:

Mouse

宿主来源:

Rabbit

实验应用:

同种型:

Rabbit Ig

克隆性:

Polyclonal

纯化方式:

This antibody is purified through a protein A column, followed by peptide affinity purification.

偶联:

Unconjugated

产品浓度:

batch dependent

保存温度:

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

Supplied in PBS with 0.09% (W/V) sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. PRR5 plays an important role in regulation of PDGFRB expression and in modulation of platelet-derived growth factor signaling. May act as a tumor suppressor in breast cancer (By similarity).

Accession #:

Q812A5

您可能感兴趣的产品

sPLA2 (human Type IIA) Polyclonal Antibody - Purified IgG

货号：45805

PAD3 Polyclonal Antibody

货号：33913

Growth Hormone (rat) Polyclonal Antibody for IHC

货号：C03904.25 µl

Goat Anti-ImmunoglobulinG (mouse) Polyclonal Antibody

货号：C03757.10 ml

Goat Anti-ImmunoglobulinG (rat) Polyclonal Antibody