官网链接
折扣/货期| 货号：V5765-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V5765-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MRC1 Antibody / Macrophage mannose receptor 1 / MRC1L1
产品描述:
CD206, also known as macrophage mannose receptor type C (MMR, MRC1, MRC1L1), is a type I membrane receptor protein. It is an phagocytic and endocytic receptor that can recognize carbohydrate ligands in target molecules. The extracellular portion of the protein includes eight C-type carbohydrate recognition domains (CRD) which are clustered together to achieve higher affinity binding to saccharides. CD206 is found on macrophages and on endothelial cells of the liver and is the only known example of a C-type lectin that contains multiple C-type CRDs. CD206 mediates the endocytosis of glycoproteins by macrophages and binds high-mannose structures on the surface of potentially pathogenic viruses, fungi and bacteria enabling them to be neutralized by phagocytic engulfment. During inflammation, CD206 is crucial for rapid clearance of several mannose-bearing serum glycoproteins but does not regulate the initiation of inflammation. CD206 is primarily expressed in mature tissue macrophages and immature dendritic cells, as well as hepatic and lymphatic endothelial cells, retinal pigmental epithelium (RPE) and mesangial cells.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
Mouse IgG2b, kappa
免疫原:
A portion of amino acids 1-200 from human Macrophage mannose receptor 1 protein was used as the immunogen for the MRC1 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
MRC1/9454
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the MRC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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