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折扣/货期| 货号：10010412-1 mg | 规格：1 mg | 目录价：￥536 |
| 货号：10010412-10 mg | 规格：10 mg | 目录价：￥2291 |
| 货号：10010412-5 mg | 规格：5 mg | 目录价：￥1286 |
| 货号：10010412-50 mg | 规格：50 mg | 目录价：￥7517 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MRE-269
别名:
ACT-333679
产品描述:
An IP receptor agonist and active metabolite of NS 304; binds to the IP receptor (Ki = 20 nM); increases cAMP levels in human PASMCs in a concentration-dependent manner; selective for the IP receptor over the DP receptor (IC50 = 2.6 µM), EP1, EP2, EP3, and EP4 receptors (IC50s = >10, 5.8, >10, and 4.9 µM, respectively), FP receptor (IC50 = >10 µM), and TP receptor (IC50 = >10 µM); induces vasodilation equally in both large and small isolated rat pulmonary arteries in a concentration-dependent manner; inhibits ADP-induced platelet aggregation in isolated human and rat platelet-rich plasma (IC50s = 0.21 and 10 µM, respectively); reduces PDGF-induced proliferation of primary patient-derived PASMCs from patients with CTEPH
保存温度:
-20
运输温度:
-20
预期分子量:
419.5
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
475085-57-5
分子式:
C25H29N3O3
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