| 货号:10010411-10 mg | 规格:10 mg | 目录价:¥670 |
| 货号:10010411-25 mg | 规格:25 mg | 目录价:¥1300 |
| 货号:10010411-5 mg | 规格:5 mg | 目录价:¥375 |
| 货号:10010411-50 mg | 规格:50 mg | 目录价:¥1849 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
NS 304
别名:
ACT-293987|Selexipag
产品描述:
An IP receptor agonist and a prodrug form of MRE-269; binds to the IP receptor (Ki = 260 nM for the human receptor) and induces cAMP accumulation in CHO cells expressing the human IP receptor (EC50 = 177 nM); selective for the IP receptor over DP, EP1-4, FP, and TP receptors and (Kis = >10 µM for all); inhibits the aggregation of isolated human and monkey but not dog platelet-rich plasma (IC50s = 5.5, 3.4, and >100 µM, respectively); increases femoral skin blood flow in rats at 1 or 3 mg/kg intraduodenally; increases survival and decreases right ventricular systolic pressure and hypertrophy in a rat model of monocrotaline-induced pulmonary arterial hypertension at 1 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
496.6
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
475086-01-2
分子式:
C26H32N4O4S
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