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折扣/货期| 货号：36656-1 mg | 规格：1 mg | 目录价：￥590 |
| 货号：36656-10 mg | 规格：10 mg | 目录价：￥4074 |
| 货号：36656-25 mg | 规格：25 mg | 目录价：￥8697 |
| 货号：36656-5 mg | 规格：5 mg | 目录价：￥2332 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MRK-016
产品描述:
An inverse agonist of α5 subunit-containing GABAA receptors; selectively binds to α1-, α2-, α3-, and α5 subunit-containing GABAA receptors (Kis = 0.83, 0.85, 0.77, and 1.4 nM, respectively) over those containing α4 and α6 subunits (Kis = 395 and >4,000 nM, respectively); selectively inhibits GABA-induced currents in L-M(TK-) cells expressing α5 subunit-containing GABAA receptors over those containing α1, α2, or α3 subunits; reverses LPS-induced decreases in Bdnf expression in the mouse hippocampus at 3 mg/kg; reverses LPS-induced memory consolidation deficits in mice at 3 mg/kg; enhances the performance of wild-type rats in a delayed matching-to-place water maze at 0.3, 1, and 3 mg/kg; reduces immobility in the forced swim test
保存温度:
-20
运输温度:
-20
预期分子量:
368.39342
产品形式:
A solid
纯度:
≥98%
CAS号:
342652-67-9
分子式:
C17H20N8O2
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