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折扣/货期| 货号：36639-1 mg | 规格：1 mg | 目录价：￥428.8 |
| 货号：36639-10 mg | 规格：10 mg | 目录价：￥2304.8 |
| 货号：36639-25 mg | 规格：25 mg | 目录价：￥3631.4 |
| 货号：36639-5 mg | 规格：5 mg | 目录价：￥1460.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Avacopan
别名:
CCX168
产品描述:
A C5a1 receptor antagonist (IC50 = 0.1 nM); selective for C5a1 over the C5a2 receptor and CMKLR2 (IC50s = >10,000 nM for both), as well as the C3a receptor, CMKLR1, and FPR1 (IC50s = >10,000 nM for all), and over panels of 18 chemokine receptors (IC50s = ≥6,700 nM for all), 54 other receptors at 10 µM, and five CYP isoforms (IC50s = >10,000 nM for all); reduces the migration of isolated cynomolgus monkey neutrophils at 50 nM; reduces C5a-induced increases in CD11b levels on neutrophils in isolated whole blood from human C5AR1 knock-in mice at 10 and 100 nM or at 0.075 and 0.15 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
581.643632
产品形式:
A solid
有效期:
1460
纯度:
≥95% (mixture of isomers)
CAS号:
1346623-17-3
分子式:
C33H35F4N3O2
促销活动
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