MRP8 Antibody / Multidrug resistance-associated protein 8 / ABCC11-单抗-深圳欣博盛生物科技有限公司

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MRP8 Antibody / Multidrug resistance-associated protein 8 / ABCC11

品牌：NSJ Bio

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说明书

折扣/货期

货号：V5611-100UG	规格：100 ug	目录价：￥6652.1
货号：V5611-20UG	规格：20 ug	目录价：￥3082.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MRP8 Antibody / Multidrug resistance-associated protein 8 / ABCC11

产品描述:

ATP-binding cassette (ABC) transporters belong to an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies, designated ABC1, MDR/TAP, MRP, ALD, OABP, GCN20 and White. The complete human ABCC subfamily has 12 identified members (ABCC1-12), nine from the multidrug resistance-like subgroup, two from the sulfonylurea receptor subgroup, and the CFTR gene. The human ABCC11 gene maps to chromosome 16q12.1 and encodes a 1,382 amino acid protein. The human ABCC12 gene maps to chromosome 16q12.1 and encodes a 1,359 amino acid protein. Transcripts of ABCC11 and ABCC12 genes are present in various adult human tissues, including liver, lung and kidney, and also in several fetal tissues. Their chromosomal localization, potential function and expression patterns identify them as candidates for paroxysmal kinesigenic choreoathetosis, a disorder characterized by attacks of involuntary movements and postures, chorea and dystonia. Other inherited disorders where ABC transporters are implicated include cystic fibrosis, neurological disease, retinal degeneration, cholesterol and bile transport defects, anemia and drug response.

反应种属:

Human

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG2b, kappa

免疫原:

A recombinant fragment (within amino acids 400-600) of human ABCC11/MRP8 protein was used as the immunogen for the MRP8 antibody.

克隆性:

Monoclonal (mouse origin)