MRPS12 Antibody-多抗-深圳欣博盛生物科技有限公司

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MRPS12 Antibody

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：30-186

规格：100 ul

目录价：￥9108.45

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

MRPS12 Antibody

别名:

MRPS12, MPR-S12, MT-RPS12, RPMS12, RPS12, RPSM12

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ELISA,WB

克隆性:

Polyclonal

纯化方式:

Antibody is purified by peptide affinity chromatography method.

偶联:

Unconjugated

产品浓度:

batch dependent

保存温度:

For short periods of storage (days) store at 4˚C. For longer periods of storage, store MRPS12 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

产地:

美国

生产商:

Prosci

功能与背景:

Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPS12 is the 28S subunit protein that belongs to the ribosomal protein S12P family. The protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics.Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene; all three variants encode the same protein.

Accession #:

NP_066930

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