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折扣/货期| 货号：GTX04416 | 规格：500μl | 目录价：￥9600 |
| 货号：GTX04416-S | 规格：100μl | 目录价：￥4200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
MSH6 antibody [MSVA-906R] HistoMAX™
别名:
mutS homolog 6 , GTBP , GTMBP , HNPCC5 , HSAP , p160
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
<b>Highly recommended for IHC-P in human tissues.</b>
同种型:
IgG
免疫原:
Recombinant fragment (around aa 1-100) of human MSH6 protein
克隆性:
Monoclonal
克隆号:
MSVA-906R
纯化方式:
Protein A/G purified
偶联:
Unconjugated
产品浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA (Please contact us for PBS only format), 0.05% sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
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