| 货号:SIH-568-50MG | 规格:50 mg | 目录价:¥907.2 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Mycophenolate mofetil
别名:
6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-(4-morpholinyl)ethyl ester
产品描述:
Inosine monophosphate dehydrogenase inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
433.5
产品形式:
White powder
产地:
加拿大
功能与背景:
Mycophenolate mofetil is an immunosuppressive agent useful in prevention of organ allograft rejection (1). It is metabolized to mycophenolic acid in vivo, which acts by inhibiting the biosynthesis of guanine nucleotides via inhibition of inosine 5’-monophosphate dehydrogenase, suppressing the production of proinflammatory cytokines, nitric oxide and LDH in macrophages (2,3). It also inhibits IL-2-dependent T cell proliferation (4), and microglial and astrocytic activation reducing cell death after neuronal injury (5). It also prevents neuroinflammation.
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
128794-94-5
分子式:
C23H31NO7
溶解度:
May be dissolved in DMSO (40 mg/ml); or ethanol (4 mg/ml)
PubChem CID:
5281078
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