Nav1.7 Antibody: ATTO 390-单抗-深圳欣博盛生物科技有限公司

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Nav1.7 Antibody: ATTO 390

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SMC-314D-A390

规格：100 µg

目录价：￥4939.2

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Nav1.7 Antibody: ATTO 390

别名:

ETHA Antibody, hNE Na Antibody, NE NA Antibody, PN1 Antibody, SCN9A Antibody, voltage gated sodium channel subunit alpha Nav1 Antibody, peripheral sodium channel 1 Antibody, neuroendocrine sodium channel Antibody

产品描述:

Mouse Anti-Human Nav1.7 Monoclonal IgG1

反应种属:

Human | Mouse | Rat | Hamster

宿主来源:

Mouse

实验应用:

WB | IHC | ICC/IF | IP | AM

靶标/特异性:

Detects ~230kDa. No cross-reactivity against other Nav channels.

同种型:

IgG1

推荐稀释度:

WB (1:1000), IHC (1:1000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.

免疫原:

Fusion protein amino acids 1751-1946 (C-terminus) of human Nav1.7

免疫原种属:

Human

克隆性:

Monoclonal

克隆号:

N68/6 (Formerly sold as S68-6)

纯化方式:

Protein G Purified

偶联:

ATTO 390

产品浓度:

1 mg/ml

保存温度:

Conjugated antibodies should be stored according to the product label

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

Nav1.7 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1.7 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.7 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals (1-3).

Accession #:

NP_002968.1