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折扣/货期| 货号：AG-CR1-2900-M005 | 规格：5 mg | 目录价：￥420 |
| 货号：AG-CR1-2900-M025 | 规格：25 mg | 目录价：￥1080 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Necrostatin-1
别名:
Nec-1; MTH-Trp; MTH-DL-Tryptophan; Methyl-thiohydantoin DL-tryptophan; 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone
产品描述:
Competitive indoleamine 2,3-dioxygenase (IDO) inhibitor [1, 4, 9, 10]. Cell permeable, potent and selective necroptosis (a non-apoptotic form of programmed cell death) inhibitor [2, 5]. Showed neuroprotection in a murine model of ischemic brain injury in vivo [2, 3]. Selective and ATP-competitive receptor-interacting protein kinase 1 (RIPK1) inhibitor [6, 7]. Used in inflammatory and degenerative disease models to target RIPK1 [7, 9, 10]. Suppresses autophagy and apoptosis in murine brain injury models [8, 9]. Cardioprotective and neuroprotective [11-14].
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
259.3
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
4311-88-0
分子式:
C13H13N3OS
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